
Chunyu Wang, MD, PhD
Chunyu Wang, professor of Biological Sciences, and Chemistry and Chemical Biology at RPI, is an expert in NMR (nuclear magnetic resonance) structural biology and in structural mechanisms of Alzheimer’s disease and cancer. He obtained his MD in 1996 from Peking Union Medical College (PUMC). He was then trained in structural biology at Cornell University under the guidance of Linda Nicholson, earning a PhD in Molecular Biology and Genetics in 2000. He carried out postdoctoral work at Columbia University in Art Palmer’s group. After establishing his own research group at RPI in 2005, he developed a strong research program in structural mechanisms in protein autoprocessing and Alzheimer’s disease. Recently, his group is venturing into new and exciting areas such as drug discovery and biological sulfation. He has been awarded multiple grants from NIH and several grants for Alzheimer’s research, from Alzheimer’s Association, Warren Alpert Foundation, New York State and American Health Assistance Foundation (Now BrightFocus foundation).
Personal interests: Tennis, Chess, Piano and Aquarium; past hobbies: bridge and astrophotography
Research Associates

Nabin
Postdoctoral Associate
Nabin's expertise and research interest are in molecular biophysics of proteins involved in Alzheimer’s and cancer, as well as physical properties of lipid membranes and protein-lipid interactions. He has broad expertise in spectroscopic techniques such as fluorescence, circular dichroism, Fourier transform infrared spectroscopy and solid-state NMR. Nabin received his BS in Physics (Physics, Chemistry, Math) from Tribhuvan University, Nepal in 2010. He moved to University of Texas, Brownsville, USA in 2012 where he got his MS in Physics (Biophysics). In 2014, Nabin joined University of Central Florida (USF), Orlando, USA and received his PhD in Physics in 2019. During his PhD, he worked on the structure-function relation of the membrane pore formed by amyloid beta peptide using spectroscopic techniques including solid state NMR. He then worked as a joint-postdoctoral researcher (2019-2020) between USF and University of California, Irvine to probe the self-assembly of Reflectin (Ref2Cx4) protein that comes from the light organs of cephalopods. In 2020, Nabin joined Dr. Wang's lab here in RPI to work on single molecule kinetic studies of the mechanism of gamma-secretase and familial Alzheimer's Disease. His projects also include biophysical characterizations of tau and p53.
Nabin Kandel

James Gibson
Research Associate
James earned his BS in chemistry from Harvey Mudd College in 1995. He earned his PhD in chemistry from Penn State in 2001, where he studied solid-state NMR under Professor Karl T. Mueller. While at Penn State, he primarily worked on solid-state NMR method development and the application of solid-state NMR to glasses. James was a postdoc at the University of Washington from 2001 to 2005, where he had his first foray into biological sciences under the direction of Professors Patrick S. Stayton (bioengineering) and Gary P. Drobny (chemistry). While there, he studied the interactions and dynamics of the binding of salivary peptides to hydroxyapatite, the main mineral component of teeth using solid-state NMR. James ventured into solution-state NMR of proteins under the direction of Professor James G. Kempf in the chemistry department at RPI in 2006 and 2007, primarily working to understand how different CPMG-type sequences worked together. After that, he spent 10 years in industry performing solution-state NMR on silicone materials and their precursors. In 2018, James came back to RPI to work in Dr. Wang's research group. He studies the interactions of proteins and their binding partners with high resolution NMR spectroscopy. He is also responsible for adapting pulse sequences from other laboratories to our laboratory for use.
James Gibson

Lin Pan
Research Associate
Lin earned her BS degree in Pharmacy from Ocean University of China in 2017. Then she took a successive post graduate and doctoral program and joined Laboratory of Glycoscience and Glycotechnology (Advisor: Prof. Guangli Yu, Dean), Ocean University of China. During the graduate student period, she focused on the field of the interaction between carbohydrate and gut microbiota. She used in vitro anerobic fermentation system to investigate how human gut microbiota digest the polysaccharide into oligosaccharide. In addition, she also investigated the therapeutic effects of natural polysaccharide on colitis mouse through modulate the composition of gut microbiota. She earned her doctoral degree of medicine in 2023. She gained professional experience and skills with HPLC, LC-MS, colitis Mouse Models, culture of anaerobic bacteria and analysis of polysaccharide and oligosaccharide. In 2023, she joined Prof. Wang’s lab here in RPI out of interest in research related to NMR technology and Alzheimer's disease. Her focus is working on the protein-protein and protein-glycan interaction in Alzheimer’s disease and drug screening for Alzheimer’s disease, using NMR and SPR. She will mainly focus on the Reelin protein in the Alzheimer’s disease.
Lin Pan
Graduate Students

Dylan Mah
Graduate
Dylan Mah is a first-year doctoral student in biology who joined the Wang Lab in the Spring of 2019. After graduating from SUNY Binghamton University in 2015 with a B.S. in Cell and Molecular Biology. He spent a year working in a clinical laboratory prior to coming to RPI in the Fall of 2018. His area of research interest is the molecular biology of aging and age-related diseases, with a focus on neurodegenerative diseases such as Alzheimer’s.
Dylan Mah

Shannon Faris
Graduate
Shannon graduated from the University of New Haven with a B.S. in Chemistry and a B.S. in Forensic Science. She joined RPI in Fall of 2019 to work towards a Ph.D. in chemistry. Shannon’s current research focuses primarily in pharmacology, drug discovery and potential inhibiters of neuro-degenerative disease, with an emphasis on Alzheimer’s.
Shannon Faris

Anqesha Murray
Graduate
Anqesha is from Rochester, New York, and received her associate’s degree in Liberal Arts and Biology from Monroe Community College in 2014. She completed her bachelor’s degree in Biological Sciences with a concentration in Microbiology and Immunology and a minor in American Sign Language and Dance at the University of Rochester. She then attended Brown University as an NIH Post-Baccalaureate Research Education Program (PREP) Scholar in the Department of Molecular Microbiology and Immunology. Anqesha came to Rensselaer Polytechnic Institute (RPI) in the fall of 2020 to pursue her PhD in Biology. She projects focus on mechanisms of tau in Alzheimer's disease.
Anqesha Murray

Nathan Smith
Graduate
Nathan is from Bradford Pennsylvania. He graduated from Mount Aloysius College in the spring of 2020 with a bachelors degree in Biology with specializations in Molecular Biotechnology and Pre-Health as well as minors in Scientific Communications and Vocal Performance. He began his first year as a PhD student in the BCBP program in the fall of 2020. He will characterize the small molecules inhibitors of protein aggregation.
Nathan Smith

Paige Nowak
Graduate
Paige is born and raised in Buffalo, NY. She received her bachelor’s
degree in chemistry with a minor in Psychological Sciences at RPI in May 2022. Paige
joined the PhD program in fall 2022 and focuses on the role of Apolipoprotein E and
its isoforms in Alzheimer’s disease.
Personal interests: Playing with her puppy, watching the Buffalo Bills win, and
dancing.
Paige Nowak

Kristina Jones
Graduate
Kristina is from Murrieta, California. She graduated from California State University San Marcos in spring of 2022 with a BS degree in Biochemistry. She started at RPI in Fall 2022 as a PhD student in the BCBP program. Her current research primarily focuses on protein-protein and protein-glycan interaction with an emphasis on Alzheimer Disease.
Kristina Jones

Matthew Widdicombe
Graduate
Matt is from Albrightsville, Pennsylvania and received his B.S. in Biochemistry from Wilkes University in 2022. His undergraduate research work with Dr. Henkels involved the site-specific incorporation of fluorine-containing unnatural amino acids into GFP for use in 19F-NMR experiments. He started his PhD program in Biochemistry and Biophysics (BCBP) at RPI in the fall of 2022, where he then joined Dr. Wang's research group in the spring of 2023. The main project he works on is the characterization of the interaction between Tau protein's Proline-Rich Region II (PRR2) and Cyclophilin A (CypA) through solution NMR. He also works on other projects in the lab utilizing analytical ultracentrifugation (AUC) and the R programming language.
Matthew Widdicombe

Annan Wu
Graduate
Annan comes from China and is an exchange scholar. He obtained his Bachelor's degree in Food Science and Engineering from Beijing Forestry University and is currently pursuing his Ph.D. in Food Science and Engineering at China Agricultural University. His main focus is on the intervention effects of food-derived bioactive substances on neurodegenerative diseases such as Alzheimer's Disease (AD).
Annan Wu
Undergraduate Students

Jacob Fuhr
Undergraduate
Jacob (Class of 2025) is from Northern New Jersey and is studying Chemical Engineering and Business Management. He has been supporting the lab since March 2023, mainly under Nathan where he has been focusing on protein interactions concerning Alzheimer’s Disease. Jacob has been working with biophysical techniques, column chromatography, and cell expression, but in his free time enjoys reading, fencing, and curling.
Jacob Fuhr

Hasitha Nimmagadda
Undergraduate
She studies Biology in the Physician-Scientist Program and is in the Class of 2026. Her focus is on Alzheimer’s Disease using techniques such as SPR. She joined Dr. Wang’s lab in the Fall of 2023.
Hasitha Nimmagadda

Hannah Burr
Undergraduate
Hannah Burr is a Biological Neuroscience major on the Pre-Med track with a minor in Music Composition in the class of 2025. She has been working with graduate student Nathan Smith since Fall 2021. She has a strong interest in studying neurological diseases, Alzheimer’s Disease in particular, and is passionate about studying protein interactions through various biochemical techniques with a goal of improving the lives of those suffering.
Hannah Burr

Katie Moon
Undergraduate
She is in the Class of 2025 majoring in Computational Biology (CBIO). She has a strong interest in research in Alzheimer’s disease and biostatistics with coding and joined Dr. Wang's research lab in Fall, 2023.