Cleopatra I (c. 215 -176 BC ) was a queen of Ptolemaic Egypt , the daughter of Antiochus III and Laodice. She married Ptolemy V in 193 BC . They had two sons and a daughter. When her husband died in 180 BC , she ruled on behalf of her son Ptolemy VI until her death.
http://www.wikipedia.org/wiki/Cleopatra_I