Go to Past Members

Collaborators

RPI Collaborators

Robert Linhardt, Rensselaer Polytechnic Institute - Glycobiology Website

Jonathan Dordick, Rensselaer Polytechnic Institute - Cell-based drug discovery Website

Scott Forth, Rensselaer Polytechnic Institute - Single molecule fluorescence Website

Jennifer Hurley, Rensselaer Polytechnic Institute - Circadian rhythm Website

Marvin Bentley, Rensselaer Polytechnic Institute - vesicle transport in neurons Website

Leo Wan, Rensselaer Polytechnic Institute - Left-right symmetry Website

New York State Collaborators

Gabrielle Fredman, Albany Medical College - cellular senescence Website

Nikolaos Robakis, Mount Sinai - Alzheimer’s disease Website

William Oh, Mount Sinai - Prostate cancer

Michael Donovan, Mount Sinai - Prostate cancer

David Eliezer, Weill Cornell Medical College - IDPs in neurodegeneration Website

Ding Xu, University at Buffalo - Glycobiology

Brian Callahan, Binghamton University - Hedgehog autoprocessing Website

Sozanne Solmaz, Binghamton University - Microtubule transport Website

Yingkai Zhang, New York University - Computational biology Website

Stewart Loh, Upstate Medical University - p53

Yue-Ming Li, Memorial Sloan Kettering Center - Gamma-secretase Website

U.S. Collaborators

Jian Liu, University of North Carolina - Glycobiology

Lianchun Wang, University of South Florida - Glycobiology

Jianhan Chen, University of Massachusetts Amherst - Computational biology Website

Gal Bitan, University of California Los Angeles - Alzheimer’s disease Website

Angel Garcia, Los Alamos National Labs - Computational biology

International Collaborators

Guy Lippens, Toulouse, France - Tau protein

Iban Ubarretxena-Belandia, Biofisika Institute (UPV/EHU, CSIC), Leioa, Spain, - Intramembrane proteolysis

Thomas Shrader, University of Duisburg-Essen, Essen, Germany, - Organic and Bio-Chemistry of tweezer Website

Xiaoyu Li, Hong Kong University - DNA encoded library

Past Lab Members

Past Postdoc
Jing (Jackie) Zhao

Past: Postdoc

2018-2020

Jackie is now an associate professor at China Agriculture University in Beijing, China.

(Click for a link to his page)

Yuanyuan Xiao

Past: Research associate

2018-2020

Yuanyuan is now a senior scientist at Eurofin.

(Click for a link to his page)

Jie Fang

Past: Research associate

Jan.- July 2020

Jie is now an assistant professor at University of Michigan at Dearborn.

(Click for a link to his page)

Xinyue (Sherry) Liu

Past: Postdoc

2018-2019

Sherry is currently a postdoc at Harvard University.

(Click for a link to his page)

Zhenming Du

Past: Postdoc

2007-2012

Zhenming (Jimmy) is now the manager of NMR center at Georgia State University.

(Click for a link to his page)

Yangzhong Liu

Past: Postdoc

2005-2006

Yangzhong is now a professor at the University of Science and Technology of China.

(Click for a link to his page)

Past Graduate Students
Allison Zwarycz

Past: Graduate Student (MS)

2016-

Andrea Bisson

Past: Graduate Student (MS)

2016

Nicolina Clemente

Past: Graduate Student (PhD)

2012-2018

Nicolina carried out high presssure NMR studies of Aβ mutants (published in Chemical Communications in 2018) and s tudied a key topic in the generation of Aβ: how substrate APPTM interacts intramembrane protease. Her publication in Scientific Reports in 2018 represents the first study of substrate-intramembrane protease interaction at atomic resolution, with important implications for many diseases, such as Alzheimer’s and cancer. She is currently a postdoctoral scientist at Van Andel Research Institute, carrying out cryoEM studies of membrane proteins.

(Click for a link to her page)

Jian Xie

Past: Graduate Student (PhD)

2011-2015

Jian Xie studied the relationship between Zinc and Hedgehog signaling and discovered that Zn diffciency may be related to Hedgehog activation in cancers. This work was published in JBC and was one of most viewed papers on JBC website. Jian then went on to study the mechanism of a special process in Hedgehog signaling, called Hedgehog autoprocessing and described a new structural mechanism in a publication in JACS. He is now a postdoctoral research associate at Yale University.

David Rosenman

Past: Graduate Student (PhD)

2010-2015

David was a joint student between Angel Garcia and me. He carried out combined NMR and MD studies of Aβ, which provided unprecedented insight into the structure and dynamics of Aβ. He has published a number of high impact papers. For example, his 2013 JMB paper (Rosenman, David J., et al. "Aβ monomers transiently sample oligomer and fibril-like configurations: ensemble characterization using a combined MD/NMR approach." Journal of molecular biology 425.18 (2013): 3338-3359.) has already been cited over 120 times! He is currently a Protein Characterization Scientist at Eurofins

Christopher Connors

Past: Graduate Student (PhD)

2008-2014

Chris carried out NMR drug screening for Aβ, and he found that tranilast, an approved drug in Asia, can bind to Aβ and promote Aβ fibrillation. This is one of the early examples of drug discovery in intrinsically disordered protein (IDP) using a combined MD/NMR approach! He is currently a Senior Scientist at Xtal BioStructures Inc.

Wen Chen

Past: Graduate Student (PhD)

2007-

Wen Chen solved the NMR structure of APPTM, an important domain in the generation of Aβ, resulting in a paper in Nature Communications. This work establishes a new structural mechanism for several genetic variants of Alzheimer’s disease (AD) and has been widely cited, e.g., by the premium AD research website alzforum. He also was the first to discover the intramolecular disulfide bond at intein active site, an excellent study published in Journal of American Chemical Society. He is currently a research associate at Harvard Medical School.

Jiajing Liu

Past: Graduate Student (PhD)

2006-2010

Jiajing solved two NMR structures. We shared a strong interest in human health and diseases. After RPI, he went on to obtain an MD at Tufts Medical School and is now practising medicine in Worcester, MA.

Nikolaos Sgourakis

Past: Graduate Student (PhD)

2005

Yilin Yan

Past: Graduate Student (PhD)

2005-2008

Yilin was Dr. Wang's first graduate student and he carried out detailed NMR studies of amyloid β-peptide, a key molecule in Alzheimer’s disease. His first paper on the dynamics of Aβ, also the first paper of my lab, has been cited over 200 times now. He obtained his PhD in four years, with a total of 8 publications, including papers in Nature Medicine, Journal of American Chemical Society. He is currently Head of Protein Science in the newly established Pfizer Asia Discovery Labs in Shanghai.

Technicians and Research Associates
Eric Gamache

Past: Research Associate

2005-2009

Past Undergraduate Students
Zahabiya Campwala

Past: Undergrad Student

2019

Emma Spiegler

Past: Undergrad Student

2015-2016

Virginia Zu

Past: Undergrad Student

2015-2016

Zhongqiang Lin

Past: Undergrad Student

2014-2018

Michelle Scotile

Past: Undergrad Student

2013-2015

Emiley Tou

Past: Undergrad Student

2013-

Benjamin Daniels

Past: Undergrad Student

2011-

Amanda Labuza

Past: Undergrad Student

2010

Cate Harvey

Past: Undergrad Student

2009

Patricia Shen

Past: Undergrad Student

2008-2011

Wendy Ho

Past: Undergrad Student

2009-2011

Sheela Rao

Past: Undergrad Student

2009-2010

Ahmad Nazem

Past: Undergrad Student

2009-2010

Danielle Richardson

Past: Undergrad Student

2009-2010

Kelly Lottman

Past: Undergrad Student

2009-2010

Lucy Greetham

Past: Undergrad Student

2009-2010

Roshni Naidu

Past: Undergrad Student

2008-2010

Meredith Eger

Past: Undergrad Student

2008-2009

David Ban

Past: Undergrad Student

2008-2009

Chenhui Yao

Past: Undergrad Student

2007-2008

Aria Bryan

Past: Undergrad Student

2007-2010

Alexina Haynes

Past: Undergrad Student

2007

Abderahmane Benghanem

Past: Undergrad Student

2005

Teresa Burton

Past: Undergrad Student

2005-2007

Alice Hsu

Past: Undergrad Student

2005-2007

Past Rotation Students
William Fall

Past: Rotation Student

2019