We are an experimental cell and tissue biomechanics laboratory focused on understanding the role of mechanics in disease initiation and progression. We are currently involved in studies utilizing in vitro models of tumor growth in order to probe the relationship between tumor cells and their biomechanical environment.
What forces do tumor cells produce and exert on their surroundings and how do they differ from healthy cells? We engineer 3D in vitro environments that mimic healthy and cancerous tissue. We measure the mechanical properties of the components of these environments as well as cells and tissues using various methods such as indentation and compression testing. Observing cellular behavior in these environments provides us a window into the biomechanical functioning of the disease.
© 2015 Kristen Mills. Statements.