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Eric H. Ledet, Ph.D.

ledete@rpi.edu

(518) 276-6959

 

Associate Professor

Department of Biomedical Engineering

Rensselaer Polytechnic Institute

 

Research Scientist

R&D Service

Stratton VA Medical Center

 

Adjunct Professor

Division of Orthopaedic Surgery

Albany Medical College

 

Chief Science Officer

ReVivo Medical, LLC

 

 

 

 

 

 

Areas of Research

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

RPI Home

 

RPI Department of Biomedical Engineering

 

Orthopaedic Research Society

 

Biomedical Engineering Society

 

North American Spine Society

 

Orthopaedic Trauma Association

 

American Society for Engineering Education

 

Global Engineering Teams

 

Life Quality Solutions Incubator

 

MsM in the News:

*Bringing the Operating Room Into the Classroom.

*Here's how smart implants can help improve health outcomes.

*Relieving the Ordeal of Surgery.

*Researchers Investigate a Non-Invasive Test for Surgical Site Infections in Orthopaedic Implants.

*News Channel 13 (NBC) Coverage of Sensor Technology.

*Sensor Detects Orthopedic Implant Infections Early.

*Eric Ledet speaks about the NYCAP Research Alliance.

*Eric Ledet speaks at the Business Opportunities to Success Summit.

*Wireless implant sensor technology described in Bone Zone.

*Eric Ledet recognized as 2017 ASEE Campus Star.

Research Recognition & Awards:

*MsM team & collaborators win prestigious 2015 ISSLS Prize for spinal research.

*Best Trauma Poster 2017, Orthopaedic Research Society national meeting.

*Best Original Research Paper 2014, Journal of Sports Health.

*Best Paper - Basic Sciences 2013, North American Spine Society national meeting.

*Lemelson Prize Finalist 2013.

*Media Spotlight Award 2012, Orthopaedic Research Society national meeting.

*Top Ten Medical Breakthroughs of 2012, Consumers Digest Magazine.

 

Publications and Patents:

Drazan JF, Abdoun OT, Wassick MT, Dahle R, Beardslee L, Marcus GA, Cady NC, Ledet EH. Simple Implantable Wireless Sensor Platform to Measure Pressure and Force. Medical Engineering & Physics, 2018;59:81-7.

Ledet EH, Liddle B, Kradinova K, Harper S. Smart Implants in Orthopaedic Surgery, Improving Patient Outcomes: A Review. The Journal Innovation and Entrepreneurship in Health, 2018;5:41-51.

Peterson JM, Chlebek C, Clough AM, Wells AK, Batzinger KE, Houston JM, Kradinova K, Glennon JC, DiRisio DJ, Ledet EH. Stiffness Matters: Part II - The Effects of Plate Stiffness on Load-Sharing and the Progression of Fusion Following ACDF In Vivo. SPINE, 2018; 43(18):E1069-76.

Peterson JM, Chlebek C, Clough AM, Wells AK, Ledet EH. Stiffness Matters: Part I - The Effects of Plate Stiffness on the Biomechanics of ACDF In Vitro. SPINE, 2018; 43(18):E1061-8.

Ledet EH, Sanders GP, DiRisio DJ, Glennon JC. Load-Sharing Through Elastic Micro-Motion Accelerates Bone Formation and Interbody Fusion. The Spine Journal. 2018;18(7):1222-30.

"Intervertebral Cage and Method of Treating Vertebrae With an Intervertebral Cage." United States patent 10,105,235. Issued October 23, 2018.

"Dynamic Spinal Fixation System, Method of Use, and Spinal Fixation System Attachment Portions." United States patent 9,861,392. Issued January 9, 2018.

Kerr H, Ledet EH, Ata A, Newitt JL, Santa Barbara M, Kahanda M, Sperry E. Does Instructional Video Footage Improve Rugby Tackle Technique? International Journal of Sports Science & Coaching, 2017;6:1-13.

"Dynamic Spinal Fixation System, Method of Use, and Spinal Fixation System Attachment Portions". United States patent 9,795,414. Issued October 24, 2017.

"Dynamic Spinal Fixation System, Method of Use, and Spinal Fixation System Attachment Portions." United States patent 9,788,864. Issued October 17, 2017.

"Sensor System, Implantable Sensor and Method for Remote Sensing of a Stimulus In Vivo." United States patent 9,662,066. Issued May 30, 2017.

Peterson JM, Healey CP, Visser GJ, Crombie C, Ledet EH. Pressure Ulcer Prevention: Optimizing a Temporally Redistributing Support Interface. American Journal of Engineering and Applied Sciences, 2016;9(4):1222-31.

Dion MK, Drazan JF, Giddings S, Desai V, Cady NC, Dahle R, Roberts JT, Ledet EH. Smart Orthopaedic Implants: Application in Total Knee Arthroplasty. American Journal of Engineering and Applied Sciences, 2016;9(4):1232-38.

"Dynamic Spinal Fixation System, Method of Use, and Spinal Fixation System Attachment Portions." United States patent 9,510,871. Issued December 6, 2016.

Gullbrand SE, Peterson J, Ahlborn J, Mastropolo R, Fricker A, Roberts TT, Abousayed M, Lawrence JP, Glennon JC, Ledet EH. ISSLS Prize Winner: Dynamic Loading-Induced Convective Transport Enhances Intervertebral Disc Nutrition. SPINE, 2015; 40(15):1158-64. Awarded 2015 ISSLS Prize for spine research.

Steiner M, Kanai J, Hsu C, Ledet EH, Walczyk D, Morris J, Anderson M, Miller S, Anderson K. Preparing Engineering Students for Professional Practice: Using Capstone to Drive Continuous Improvement. International Journal of Engineering Education, 2015; 31(1):154-64.

Gullbrand SE, Peterson J, Mastropolo R, Roberts TT, Lawrence JP, Glennon JC, DiRisio DJ, Ledet EH. Low Rate Loading Induced Convection Enhances Net Transport into the Intervertebral Disc In Vivo. The Spine Journal, 2015;15:1028-33. PMID: 25500262.

Drazan JF, Gunko AA, Abdoun O, Healey C, Dion M, Cady N, Connor KP, Ledet EH. Archimedean Spiral Pairs With No Electrical Connections as Passive Wireless Implantable Force Sensors. The Journal of Biomedical Technology and Research, 2014; 6000104:1-8. PMCID: PMC4945132.

Gullbrand SE, Peterson J, Mastropolo R, Lawrence JP, Lopes L, Lotz J, Ledet EH. Drug-Induced Changes to the Vertebral Endplate Vasculature Affect Transport Into the Intervertebral Disc In Vivo. The Journal of Orthopaedic Research 2014; 32(12):1694-1700. PMID: 25185989.

Wachs RA, Ellstein D, Drazan J, Healey CP, Uhl RL, Connor KA, Ledet EH. Elementary Implantable Force Sensor for Smart Orthopaedic Implants. Advances in Biosensors and Bioelectronics 2013;2(4):57-64. PMCID: PMC4037930. PMID: 24883335.

Dezman ZDW, Ledet EH, Kerr HA. Neck Strength Imbalance Correlates With Increased Head Acceleration in Soccer Heading. Sports Health Journal, 2013; 5(4):320-6. Awarded 2014 Sports Health T. David Sisk Award for Best Original Research Paper.

Korduba LA, Grabowsky MBM, Uhl RL, Hella MM, Ledet EH. Radiofrequency Identification as a Testbed for Integration of Low Frequency Radio Frequency Sensors Into Orthopaedic Implants. Journal of Medical Devices, 2013; 7(1):011008-8.

Zhao L, Tanjung N, Swarnkar G, Ledet EH, Yokota H. Regulation of eIF2a Phosphorylation in Hindlimb-Suspended and STS-135 Space-Flown Mice. Advances in Space Research, 2012; 50:576-83.

Ledet EH, DíLima D, Westerhoff P, Szivek JA, Wachs RA, Bergmann G. Implantable Sensor Technology: From Research to Clinical Practice. Journal of the American Academy of Orthopaedic Surgery. 2012; 20:383-392. PMID: 22661568.

Zhang P, Jiang C, Ledet EH, Yokota. H. Loading- and Unloading-Driven Regulation of Phosphorylation of eIF2α. Biological Sciences in Space 2011; 25(1):3-6.

Bellapianta J, Dow K, Pallotta N, Hospodar PP, Uhl RL, Ledet EH. Threaded Screw Head Inserts Improve Locking Plate Biomechanical Properties. Journal of Orthopaedic Trauma, 2011;25(2):65-71. PMID: 21245707.

Ledet EH, Carl AL, Glennon JC, Jeshuran W, De Deyne P, Belden C. Small Intestinal Submucosa for Anular Repair: Long Term Response In An In Vivo Sheep Model. SPINE, 2009; 34(14):1457-63.

Ledet EH, Carl AL, Cragg A. A Novel Lumbosacral Axial Fixation Technique. Expert Review of Medical Devices, 2006; 3(3); 327-34.

Ledet EH, Tymeson MP, Salerno S, Carl AL, Cragg A. Biomechanical Evaluation of a Novel Lumbosacral Axial Fixation Device. Journal of Biomechanical Engineering, 2005; 127:929-33.

Singh K, Ledet EH, Carl AL. Intradiscal Therapy: A Review of Current Treatment Modalities. SPINE, 2005; 30(17): S20-6.

Ledet EH, Tymeson MP, DiRisio DJ, Cohen B, Uhl RL. Direct Real Time Measurement of In Vivo Forces in the Lumbar Spine. The Spine Journal, 2005; 5(1):85-94. PMID: 15653089.

Panjabi MM, Goel VK, Cripton PA, Dooris AP, Ledet EH, Moumene M, Natarajan RN, Patwardhan AG, Sengupta DK, Serhan HA, Wilke HJ. Biomechanical Terminology and Concepts. Roundtables in Spine Surgery, 2004; 1(1):99-106.

Goel VK, Cripton PA, Dooris AP, Ledet EH, Moumene M, Natarajan RN, Panjabi MM, Patwardhan AG, Sengupta DK, Serhan HA, Wilke HJ. Spine Biomechanics: Roundtable Discussion. Roundtables in Spine Surgery, 2004; 1(1):59-95.

Carl AL, Ledet EH, Yuan H, Sharan A. New Developments in Nucleus Pulposus Replacement Technology. The Spine Journal, 2004; 4(6):325S-329S.

Ledet EH, Carl AL, DiRisio DJ, Tymeson MP, Andersen LB, Slivka MA, Serhan H. A Pilot Study to Evaluate The Effectiveness of Small Intestinal Submucosa Used to Repair Spinal Ligaments in the Goat. The Spine Journal 2002;2:188-96.

Ledet EH, Sachs BL, Brunski JB, Gatto CE, Donzelli PS: Real Time In Vivo Loading in the Lumbar Spine. Part 1: Interbody Implant - Load Cell Design and Preliminary Results. SPINE 2000;25(20): 2595-600. PMID: 11034643