Hahn Group Publications

Journal Publications:

73. T. Omer, X. Intes, and J. Hahn. Temporal Data Set Reduction Based on D-optimality for Quantitative FLIM-FRET Imaging. PLoS ONE 10(12): e0144421 (2015) [Article, Abstract]

72. P. Zhang, W. Dai, J. Hahn, and S.P. Gilbert. Drosophila Ncd Reveals an Evolutionarily Conserved Powerstroke Mechanism for Homodimeric and Heterodimeric Kinesin-14s. PNAS 112, No. 20, pp. 6359-6364 (2015) [Article, Abstract]

71. G. Zheng, D. Howsmon, B. Zhang, J. Hahn, D. McGuinness, J. Hendler, and H. Ji. Entity Linking for Biomedical Literature. BMC Medical Informatics and Decision Making 15, No. S1, S4 (2015) [Article, Abstract]

70. S. Maiti, W. Dai, R. Alaniz, J. Hahn, and A. Jayaraman. Mathematical Modeling of Pro- and Anti-Inflammatory Signaling in Macrophages. Processes 3, No. 1, pp. 1-18 (2015) [Article, Abstract]

69. W. Dai, J. Kang, and J. Hahn. Reconstruction of Transcription Factor Profiles via Dynamic Optimization and Tikhonov Regularization. AIChE Journal 60, No. 11, pp. 3754-3761 (2014) [Article, Abstract]

68. T. Omer, L. Zhao, X. Intes, and J. Hahn. Reduced Temporal Sampling Effect on Time-domain Fluorescence Lifetime FRET Accuracy. Journal of Biomedical Optics 19, No. 8, 086023 (2014) [Article, Abstract]

67. J. Liu, W. Dai, and J. Hahn. Mathematical Modeling and Analysis of Crosstalk between MAPK Pathway and Smad-dependent TGF-b Signal Transduction. Processes 2, No. 3, pp. 570-595 (2014) [Article, Abstract]

66. S. Tututi-Avila, A. Jimenez-Gutierrez, and J. Hahn. Control Analysis of an Extractive Dividing-Wall Column used for Ethanol Dehydration. Chemical Engineering & Processing: Process Intensification 82, pp. 88-100 (2014) [Article, Abstract]

65. V. Mahindrakar and J. Hahn. Dynamics and Control of Benzene Hydrogenation via Reactive Distillation. Journal of Process Control 24, No. 3, pp. 113-124 (2014) [Article, Abstract]

64. S. Tututi-Avila, A. Jimenez-Gutierrez, and J. Hahn. Analysis of Multi-loop Control Structures for Dividing-Wall Distillation Columns Using a Fundamental Model. Processes 2, No. 1, pp. 180-199 (2014) [Article, Abstract]

63. W. Dai, L. Bansal, D. Word, and J. Hahn. Parameter Set Selection for Dynamic Systems under Uncertainty via Dynamic Optimization and Hierarchical Clustering. AIChE Journal 60, No. 1, pp. 181-192 (2014) [Article, Abstract]

62. A. Bhadouria, M. Sorci, M. Gu, G. Belfort, and J. Hahn. Optimization of Membrane Separation Processes for Protein Fractionation. Industrial & Engineering Chemistry Research 53, No. 13, pp. 5103-5109 (2014) [Article, Abstract]

61. W. Dai, D. Word, and J. Hahn. Modeling and Dynamic Optimization of Fuel-grade Ethanol Fermentation Using Fed-batch Process. Control Engineering Practice,22 pp. 231-241 (2014) [Article, Abstract]

60. L. Bansal, R. Nelson, E. Yang, A. Jayaraman, and J. Hahn. Experimental Design of Systems Involving Multiple Fluorescent Protein Reporters. Chemical Engineering Science 101, pp. 191-198 (2013) [Article, Abstract]

59. C. Kravaris, J. Hahn, and Y. Chu. Advances and Selected Recent Developments in State and Parameter Estimation. Computers & Chemical Engineering 51, pp. 111-123 (2013) [Article, Abstract]

58. M. Serpas, Y. Chu, and J. Hahn. Fault Detection Approach for Systems Involving Soft Sensors. Journal of Loss Prevention in the Process Industries 26, No. 3, pp 443-452 (2013) [Article, Abstract]

57. J. Hahn, C. Scali, M. Kano, C. Georgakis, L. Bergh, J.A. Moreno Perez, and K. Asano. Editorial: Special Issue Containing Selected Papers of the 18th IFAC World Congress. Journal of Process Control 23, No. 2, pp 99 (2013) [Article]

56. Y. Chu and J. Hahn. Necessary Condition for Applying Experimental Design Criteria to Global Sensitivity Analysis Results. Computers & Chemical Engineering 48, pp. 280-292 (2013) [Article, Abstract]

55. M. Serpas, G. Hackebeil, C. Laird, and J. Hahn. Sensor Location for Nonlinear Dynamic Systems via Observability Analysis and Max-Det Optimization. Computers & Chemical Engineering 48, pp. 105-112 (2013) [Article, Abstract]

54. D.J. Munoz-Pinto, X. Qu, L. Bansal, H.N. Hayenga, J. Hahn, and M.S. Hahn. Relative Impact of Form-induced Stress vs. Uniaxial Alignment on Multipotent Stem Cell Myogenesis. Acta Biomaterialia 11, No. 11, pp. 3974-3981 (2012) [Article, Abstract]

53. L. Bansal, Y. Chu, C. Laird, and J. Hahn. Regularization of Inverse Problems to Determine Transcription Factor Profiles from Fluorescent Reporter Systems. AIChE Journal 58, No. 12, pp. 3751-376 (2012) [Article, Abstract]

52. Z. Huang, Y. Chu, and J. Hahn. Computing Transcription Factor Distribution Profiles from Green Fluorescent Protein Reporter Data. Chemical Engineering Science 68, No. 1, pp. 340-354 (2012) [Article, Abstract]

51. Y. Chu and J. Hahn. Generalization of a Parameter Set Selection Procedure based upon Orthogonal Projections and the D-Optimality Criterion. AIChE Journal 58, No. 7, pp. 2085-2096 (2012) [Article, Abstract]

50. Y. Chu, M. Serpas, and J. Hahn. State-preserving Nonlinear Model Reduction Procedure. Chemical Engineering Science 66, No. 17, pp. 3907-3913 (2011) [Article, Abstract]

49. Y. Chu, Z. Huang, and J. Hahn. Global Sensitivity Analysis Procedure Accounting for Effect of Available Experimental Data. Industrial & Engineering Chemistry Research 50, No. 3, pp. 1294-1304 (2011) [Article, Abstract]

48. C. Moya, Z. Huang, P. Cheng, A. Jayaraman, and J. Hahn. Investigation of IL-6 and IL-10 Signaling via Mathematical Modeling. IET Systems Biology 5, No. 1, pp. 15-26 (2011) [Article, Abstract]

47. Z. Huang, C. Moya, A. Jayaraman, and J. Hahn. Using the Tet-On System to Develop a Procedure for Extracting Transcription Factor Activation Dynamics. Molecular BioSystems 6, No. 10, pp. 1883-1889 (2010) [Article, Abstract]

46. R. Kaunas, Z. Huang, and J. Hahn. A Kinematic Model Coupling Stress Fiber Dynamics with JNK Activation in Response to Matrix Stretching. Journal of Theoretical Biology 264, No. 2, pp. 593-603 (2010) [Article, Abstract]

45. Y. Chu and J. Hahn. Quantitative Optimal Experimental Design using Global Sensitivity Analysis via Quasi Linearization. Industrial & Engineering Chemistry Research 49, No. 17, pp. 7782-7794 (2010) [Article, Abstract]

44. Z. Huang, Y. Chu, and J. Hahn. Model Simplification Procedure for Signal Transduction Pathway Models: An Application to IL-6 Signaling. Chemical Engineering Science 65, No. 6, pp. 1964-1975 (2010) [Article, Abstract]

43. Z. Huang, Y. Chu, B. Cunha, and J. Hahn. Generalization of a Procedure for Computing Transcription Factor Profiles. IET Systems Biology 4, No. 2, pp. 108-118 (2010) [Article, Abstract]

42. Y. Chu, Z. Huang, and J. Hahn. Improving Prediction Capabilities of Complex Dynamic Models via Parameter Selection and Estimation. Chemical Engineering Science 64, No. 19, pp. 4178-4185 (2009) [Article, Abstract]

41. A. McArdle, U. Kruger, and J. Hahn. Multivariate Statistical Analysis Applied to an IL6 Signal Transduction Model in Hepatocytes. Statistics in Medicine 28, No. 19, pp. 2401-2434 (2009) [Article, Abstract]

40. Y. Chu and J. Hahn. Parameter Set Selection via Clustering of Parameters into Pair-wise Indistinguishable Groups of Parameters. Industrial & Engineering Chemistry Research 48, No. 13, pp. 6000-6009 (2009) [Article, Abstract]

39. C. Qu and J. Hahn. Process Monitoring and Parameter Estimation via Unscented Kalman Filtering. Journal of Loss Prevention in the Process Industries 22, No. 6, pp. 703-709 (2009) [Article, Abstract]

38. Z. Huang and J. Hahn. Fuzzy Modeling of Signal Transduction Networks. Chemical Engineering Science 64, No. 9, pp. 2044-2056 (2009) [Article, Abstract]

37. C. Qu and J. Hahn. Computation of Arrival Cost for Moving Horizon Estimation via Unscented Kalman Filtering. Journal of Process Control 19, No. 2, pp. 358-363 (2009) [Article, Abstract]

36. Z. Huang, F. Senocak, A. Jayaraman, and J. Hahn. Integrated Modeling and Experimental Approach for Determining Transcription Factor Profiles from Fluorescent Reporter Data. BMC Systems Biology 2:64 (2008) [Article, Abstract]

35. Y. Chu and J. Hahn. Integrating Parameter Selection with Experimental Design under Uncertainty for Nonlinear Dynamic Systems. AIChE Journal 54, No. 9, pp. 2310-2320 (2008) [Article, Abstract]

34. J. Hahn, M. Moennigmann, and W. Marquardt. On the Use of Bifurcation Analysis for Robust Controller Tuning for Nonlinear Systems. Journal of Process Control 18, No. 3-4, pp. 408-420 (2008) [Article, Abstract]

33. J. Brewer, Z. Huang, A.K. Singh, M. Misra, and J. Hahn. Sensor Network Design via Observability Analysis and Principal Component Analysis. Industrial & Engineering Chemistry Research 46, No. 24, pp. 8026-8032 (2007) [Article, Abstract]

32. Y. Chu and J. Hahn. Parameter Set Selection for Estimation for Nonlinear Dynamic Systems. AIChE Journal 53, No. 11, pp. 2858-2870 (2007) [Article, Abstract]

31. Y. Chu, A. Jayaraman, and J. Hahn. Parameter Sensitivity Analysis of IL-6 Signaling Pathways. IET Systems Biology 1, No. 6, pp. 342-352 (2007) [Article, Abstract]

30. J. Hahn. Review: Introduction to Process Control. Journal of Process Control 17, No. 2, pp. 187-188 (2007). [Article]

29. A.K. Singh, A. Jayaraman, and J. Hahn. A Case Study of Representing Signal Transduction in Liver Cells as a Feedback Control Problem. Chemical Engineering Education 41, No. 3, pp. 177-182 (2007) [Article, Abstract]

28. Y. Chu and J. Hahn. Development of Parameter Sensitivity Analysis Techniques for Studying Interactions among Parameters and Application to Systems Biology. Dynamics of Continuous, Discrete and Impulsive Systems 14, No. S2, pp 220-226 (2007) [Article, Abstract]

27. A.K. Singh, A. Jayaraman, and J. Hahn. Modeling Regulatory Mechanisms in IL-6 Signal Transduction in Hepatocytes. Biotechnology & Bioengineering 95, No. 5, pp. 850-862 (2006) [Article, Abstract]

26. C. Sun and J. Hahn. Parameter Reduction for Stable Dynamical Systems based on Hankel Singular Values and Sensitivity Analysis. Chemical Engineering Science 61, No. 16, pp. 5393-5403 (2006) [Article, Abstract]

25. A.K. Singh and J. Hahn. Sensor Location for Stable Nonlinear Dynamic Systems: Multiple Sensor Case. Industrial & Engineering Chemistry Research 45, No. 10, pp. 3615-3623 (2006) [Article, Abstract]

24. J. Hahn. Review: Handbook of PI and PID Controller Tuning Rules. IEEE Control Systems Magazine 26, No. 1, pp. 92-93 (2006) [Article]

23. Y. Zhou, J. Hahn, and M.S. Mannan. Process Monitoring Based on Classification Tree and Discriminant Analysis. Reliability Engineering & System Safety 91, No. 5, pp. 546-555 (2006) [Article, Abstract]

22. W.H. Jang, J. Hahn, and K.R. Hall. The Design Benefit Method: A Framework for Allocating Joint Costs among Joint Products. Hydrocarbon Processing, January, (2006) [Article, Abstract]

21. S. Rajaraman, J. Hahn, and M.S. Mannan. Sensor Fault Diagnosis for Nonlinear Processes with Parametric Uncertainties. Journal of Hazardous Materials 130, No. 1-2, pp. 1-8 (2006) [Article, Abstract]

20. C. Sun and J. Hahn. Model Reduction in the Presence of Uncertainty in Model Parameters. Journal of Process Control 16, No. 6, pp. 645-649 (2006) [Article, Abstract]

19. W.H. Jang, K.R. Hall, and J. Hahn. Genetic/Quadratic Search Algorithm for Plant Economic Optimizations Using a Process Simulator. Computers and Chemical Engineering 30, No. 2, pp. 285-294 (2005) [Article, Abstract]

18. U. Kruger, D. Antory, J. Hahn, G.W. Irwin, and G. McCullough. Introduction of a Nonlinearity Measure for Principal Component Models. Computers and Chemical Engineering 29, No. 11-12, pp. 2355-2362 (2005) [Article, Abstract]

17. A.K. Singh and J. Hahn. State Estimation for High-Dimensional Chemical Processes. Computers and Chemical Engineering 29, No. 11-12, pp. 2326-2334 (2005) [Article, Abstract]

16. A.K. Singh and J. Hahn. Determining Optimal Sensor Locations for State and Parameter Estimation for Stable Nonlinear Systems. Industrial & Engineering Chemistry Research 44, No. 15, pp. 5645-5659 (2005) [Article, Abstract]

15. C. Sun and J. Hahn. Reduction of Differential-Algebraic Equation Systems via Projections and System Identification. Journal of Process Control 15, No. 6, pp. 639-650 (2005) [Article, Abstract]

14. G. Froment, M. El-Halwagi, J. Hahn, and M.S. Mannan. Foreword: Selected Papers Presented at the Symposium on Modeling of Complex Processes. Computers and Chemical Engineering 29, No. 11-12, pp. 2265 (2005) [Article]

13. M. Guay, R. Dier, J. Hahn, and P.J. McLellan. Effect of Process Nonlinearity on Linear Quadratic Regulator Performance. Journal of Process Control 15, No. 1, pp. 113-123 (2005) [Article, Abstract]

12. S. Rajaraman, J. Hahn, and M.S. Mannan. A Methodology for Fault Detection, Isolation, and Identification for Nonlinear Processes with Parametric Uncertainties. Industrial & Engineering Chemistry Research 43, No. 21, pp. 6774-6786 (2004) [Article, Abstract]

11. J. Hahn. Review: Handbook of PI and PID Controller Tuning Rules. Journal of Process Control 14, No. 5, pp. 591 (2004) [Article]

10. J. Hahn, M. Monnigmann, and W. Marquardt. A Method for Robustness Analysis of Controlled Nonlinear Systems. Chemical Engineering Science 59, pp. 4325-4338 (2004) [Article, Abstract]

9. Y. Zhou, J. Hahn, and M.S. Mannan. Fault Detection and Classification in Chemical Processes Based on Neural Networks with Feature Extraction. ISA Transactions 42, No. 4, pp. 651-664 (2003) [Article, Abstract]

8. J. Hahn, T.F. Edgar, and W. Marquardt. Controllability and Observability Covariance Matrices for the Analysis and Order Reduction of Stable Nonlinear Systems. Journal of Process Control 13, No. 2, pp. 115-127 (2003) [Article, Abstract]

7. J. Hahn and T.F. Edgar. An Improved Method for Nonlinear Model Reduction Using Balancing of Empirical Gramians. Computers and Chemical Engineering 26, No. 10, pp. 1379-1397 (2002) [Article, Abstract]

6. J. Hahn, S. Lextrait, and T.F. Edgar. Nonlinear Balanced Model Residualization via Neural Networks. AIChE Journal 48, No. 6, pp. 1353-1357 (2002) [Article, Abstract],

5. J. Hahn and T.F. Edgar. Balancing Approach to Minimal Realization and Model Reduction of Stable Nonlinear Systems. Industrial & Engineering Chemistry Research 41, No. 9, pp. 2204-2212 (2002) [Article, Abstract]

4. J. Hahn, T. Edison, and T.F. Edgar. Adaptive IMC Control for Drug Infusion for Biological Systems. Control Engineering Practice 10, No. 1, pp. 45-56 (2002) [Article, Abstract]

3. J. Hahn and T.F. Edgar. A Gramian Based Approach to Nonlinearity Quantification and Model Classification. Industrial & Engineering Chemistry Research 40, No. 24, pp. 5724-5731 (2001) [Article, Abstract]

2. J. Hahn, T. Edison, and T.F. Edgar. A Note on Stability Analysis using Bode Plots. Chemical Engineering Education 35, No. 3, pp. 208-211 (2001) [Article, Abstract]

1. T.F. Edgar, S.W. Butler, J. Campbell, C. Pfeiffer, C. Bode, S.B. Hwang, K.S. Balakrishnan, and J. Hahn. Automatic Control in Microelectronics Manufacturing: Practices, Challenges, and Possibilities. Automatica 36, No. 11, pp. 1567-1603 (2000) [Article, Abstract]


Books and Book Chapters:

12. J. Hahn and T.F. Edgar. Process Control. Kirk-Othmer Encyclopedia of Chemical Technology, 6th edition, John Wiley & Sons, New York (2014) [Abstract]

11. W. Dai and J. Hahn. Batch Control and Trajectory Optimization in Fuel Ethanol Production. The Impact of Control Technology, T. Samad and A. Annaswamy (editors), IEEE Control Systems Society (2014) [Online Edition]

10. Y. Chu and J. Hahn. Optimal Experiment Design, Signal Transduction Pathways. Encyclopedia of Systems Biology, Springer, Heidelberg, Germany (2011) [Online Edition]

9. A. Jayaraman and J. Hahn (editors). Methods in Bioengineering: Systems Analysis of Biological Networks. ISBN-13: 978-1-59693-406-1, Artech House, Boston, Massachusetts (2009) [Book Information]

8. Z. Huang and J. Hahn. Comparison of Algorithms for Analyzing Fluorescent Microscopy Images and Computation of Transcription Factor Profiles. Methods in Bioengineering: Systems Analysis of Biological Networks, Artech House, Boston, Massachusetts, pp. 33-56 (2009) [Abstract]

7. T.F. Edgar and J. Hahn. Process Automation. Handbook of Automation, Springer-Verlag, New York, pp. 529-543 (2009) [Online Edition, Outline]

6. J. Hahn and T.F. Edgar. Process Control. Kirk-Othmer Concise Encyclopedia of Chemical Technology, 5th edition, John Wiley & Sons, New York (2007) [Abstract]

5. S. Rajaraman, U. Kruger, M.S. Mannan, and J. Hahn. A New Sensor Fault Diagnosis Technique Based Upon Subspace Identification and Residual Filtering. Computational Intelligence, LNAI, Vol. 4114, Springer, Heidelberg, Germany, pp. 990-998 (2006) [Online Edition, Abstract]

4. T.F. Edgar and J. Hahn. Process Dynamics and Control. The Electronics Handbook, 3rd edition, CRC Press, Boca Raton, Florida, pp. 1974-1995 (2004) [Abstract]

3. M. Monnigmann, J. Hahn, and W. Marquardt. Towards Constructive Nonlinear Dynamics - Case Studies from Chemical Engineering. Nonlinear Dynamics of Production Systems, Wiley-VCH, Weinheim, Germany, pp. 503-526 (2004) [Abstract]

2. J. Hahn and T.F. Edgar. Process Control. Kirk-Othmer Encyclopedia of Chemical Technology, 5th edition, John Wiley & Sons, New York (2003) [Online Edition, Abstract]

1. J. Hahn and T.F. Edgar. Process Control Systems. Encyclopedia of Physical Science and Technology, 3rd edition, Vol. 13, Academic Press, San Diego, California, pp. 111-126 (2001) [Abstract]


Conference Papers & Presentations (peer-reviewed conference papers in proceedings):

27. J. Hahn and D. Howsmon. Regularization Techniques for Biochemical Reaction Networks. Proceedings of the FOSBE 2015, Cambridge, Massachusetts (2015) Invited Plenary Presentation [Paper, Abstract]

26. W. Dai, L. Bansal, and J. Hahn. Parameter Set Selection for Signal Transduction Pathway Models including Uncertainties. Proceedings of the 2014 IFAC World Congress, Cape Town, South Africa (2014) Invited Presentation [Paper, Abstract]

25. W. Dai and J. Hahn. Computing Optimal Operating Condition Profiles for Fed-Batch Fermentation of Fuel-Grade Ethanol. Proceedings of the 2013 European Control Conference, Zuerich, Switzerland (2013) [Paper, Abstract]

24. L. Bansal, Y. Chu, C. Laird, and J. Hahn. Determining Transcription Factor Profiles from Fluorescent Reporter Systems involving Regularization of Inverse Problems. Proceedings of the 2012 American Control Conference, Montreal, Canada, pp. 2725-2730 (2012) [Paper, Abstract]

23. C. Kravaris, Y. Chu, and J. Hahn. Advances and Selected Recent Developments in State and Parameter Estimation. Proceedings of Chemical Process Control 8, Savannah, Georgia (2012) Invited Plenary Presentation [Paper, Abstract]

22. R. Dunia and J. Hahn. HIV Epidemic Model with Heterogeneous Infected Class. Proceedings of the 2011 IFAC World Congress, Milano, Italy, pp. 14159-14164 (2011) [Paper, Abstract]

21. Z. Huang, Y. Chu, and J. Hahn. Derivation of Simplified Signal Transduction Pathway Models: Application to IL-6 Signaling. Proceedings of the 2010 American Control Conference, Baltimore, Maryland, pp. 5131-5136 (2010) Invited Presentation [Paper, Abstract]

20. Z. Huang, C. Moya, P. Cheng, A. Jayaraman, and J. Hahn. In Silico Investigation of IL-6 and IL-10 Signaling in Steatosis. Proceedings Foundations of Systems Biology in Engineering 2009, Denver, Colorado, pp. 28-31 (2009) [Paper, Abstract]

19. Z. Huang, Y. Chu, and J. Hahn. Derivation of a Reduced IL-6 Signal Transduction Model. Proceedings Foundations of Systems Biology in Engineering 2009, Denver, Colorado, pp. 32-35 (2009) [Paper, Abstract]

18. Z. Huang, F. Senocak, A. Jayaraman, and J. Hahn. Solution of Inverse Problems for Obtaining Protein Concentrations from Fluorescent Microscopy Images. Proceedings of the 2009 American Control Conference, St. Louis, Missouri, pp. 1688-1693 (2009) [Paper, Abstract]

17. Y. Chu and J. Hahn. Selection of Parameter Sets and Design of Experiments for Estimation of Nonlinear Dynamic Systems. Proceedings of the 2008 IFAC World Congress, Seoul, Korea, pp. 5545-5550 (2008) [Paper, Abstract]

16. Z. Huang and J. Hahn. Fuzzy Modeling of Signal Transduction Networks. Proceedings of the 2008 IFAC World Congress, Seoul, Korea, pp. 15867-15872 (2008) Invited Presentation [Paper, Abstract]

15. Z. Huang, Y. Chu, F. Senocak, A. Jayaraman, and J. Hahn. Model Update of Signal Transduction Pathways in Hepatocytes based upon Sensitivity Analysis. Proceedings Foundations of Systems Biology in Engineering 2007, Stuttgart, Germany, pp. 45-50 (2007) Plenary Presentation [Paper, Abstract]

14. A. McArdle, U. Kruger, T. Littler, and J. Hahn. Analysis of IL6 Signal Transduction Model using Reduced Rank Regression. Proceedings of the 2007 IEEE Conference on Systems and Control, Singapore (2007) [Paper, Abstract]

13. A.K. Singh and J. Hahn. Effect of Finite-Dimensional Approximations on Observability Analysis of Distributed Parameter Models. Proceedings of the DYCOPS 2007, Cancun, Mexico, Vol. 3, pp. 199-204 (2007) [Paper, Abstract]

12. A.K. Singh, A. Jayaraman, and J. Hahn. Effect of SHP-2, SOCS3, and PP2 on IL-6 Signal Transduction in Hepatocytes. Proceedings of the 2006 American Control Conference, Minneapolis, Minnesota, pp. 3771-3776 (2006) [Paper, Abstract]

11. A.K. Singh and J. Hahn. Sensor Location for Stable Nonlinear Systems: Placing Multiple Sensors. Proceedings Chemical Process Control 7, Lake Louise, Canada (2006) Best Contributed Paper Award [Paper, Abstract]

10. A.K. Singh, A. Jayaraman, and J. Hahn. Mathematical Model of IL-6 Signal Transduction in Hepatocytes. Proceedings Foundations of Systems Biology in Engineering 2005, Santa Barbara, pp. 188-192 (2005) [Paper, Abstract]

9. S. Rajaraman, M.S. Mannan, and J. Hahn. A Parametric Approach to Robust State and Parameter Estimation for a Certain Class of Nonlinear Systems. Proceedings of the 2005 American Control Conference, Portland, pp. 3610-3615 (2005) Best Paper Presentation in Session Award [Paper, Abstract]

8. A.K. Singh and J. Hahn. On the Use of Empirical Gramians for Controllability and Observability Analysis. Proceedings of the 2005 American Control Conference, Portland, pp. 140-141 (2005) Best Paper Presentation in Session Award [Paper, Abstract]

7. C. Sun and J. Hahn. On the Use of Partial Least Squares (PLS) and Balancing for Nonlinear Model Reduction. Proceedings of the 2005 American Control Conference, Portland, pp. 2572-2577 (2005) Best Paper Presentation in Session Award [Paper, Abstract]

6. A. Singh and J. Hahn. Optimal Sensor Location for Nonlinear Dynamic Systems via Empirical Gramians. Proceedings of the DYCOPS 2004, Boston (2004) [Paper, Abstract]

5. J. Hahn, M. Monnigmann, and W. Marquardt. Robust Tuning of Feedback Linearizing Controllers via Bifurcation Analysis. Proceedings of the ADCHEM 2003, Hong-Kong, China, pp. 525-530 (2003) [Paper, Abstract]

4. M. Monnigmann , J. Hahn, and W. Marquardt. Towards Constructive Nonlinear Dynamics - Case Studies from Chemical Engineering. Proc. 4th Int. Symp. "Investigation of Nonlinear Dynamic Effects in Production Systems", Chemnitz, Germany (2003) [Slides, Abstract]

3. J. Hahn, U. Kruger, and T.F. Edgar. Application of Model Reduction for Model Predictive Control. Proceedings of the 2002 IFAC World Congress, Barcelona, Spain (2002) [Paper, Abstract]

2. R. Good, J. Hahn, T. Edison, and S.J. Qin. Drug Dosage Adjustment via Run-to-Run Control. Proceedings of the 2002 American Control Conference, Anchorage, pp. 4044-4049 (2002) [Paper, Abstract]

1. J. Hahn and T.F. Edgar. Reduction of Nonlinear Models using Balancing of Empirical Gramians and Galerkin Projections. Proceedings of the 2000 American Control Conference, Chicago, pp. 2864-2868 (2000) [Paper, Abstract]


Conference Presentations (excluding presentations at conferences with proceedings):

73. D. Howsmon and J. Hahn. Generalization of a Parameter Set Selection Procedure for Nonlinear Systems. AIChE 2015 Annual Meeting, Salt Lake City, Utah (2015)

72. S. Tututi-Avila, N. Medina-Herrera, J. Hahn, and A. Jimenez-Gutierrez. Bioethanol Production: Design and Control of an Alternative Extractive Distillation System. AIChE 2015 Annual Meeting, Salt Lake City, Utah (2015)

71. T. Omer, X. Intes, and J. Hahn. Optimization Framework for Time-Gate Selection in FLIM-FRET Imaging. BMES 2015 Annual Meeting, Tampa, Florida (2015)

70. J. Hahn and D. Howsmon. Techniques for Dealing with Overparameterized Biological Pathway Models. Pre-Conference Workshop FOSBE 2015, Cambridge, Massachusetts (2015)

69. D. Howsmon, F. Cameron, N. Baysal, T.T. Ly, D.M. Maahs, B.A. Buckingham, J. Hahn, and B.W. Bequette. Infusion Set Fault Detection via Monitoring of Real-time Data over Sliding Windows. Diabetes Technology Meeting 2015, Bethesda, Maryland (2015)

68. D. Howsmon, S. Steinmeyer, R. Alaniz, A. Jayaraman, and J. Hahn. Neural Networks Elucidate T Cell Priming Conditions for Adoptive Transfer. 41st Annual Northeast Bioengineering Conference, Troy, New York (2015)

67. T. Omer, X. Intes, and J. Hahn. Sensitivity Analysis-Based Time Gate Selection Procedure for Biexponential Fluorescence Imaging. 41st Annual Northeast Bioengineering Conference, Troy, New York (2015)

66. A. Sinkoe, A. Julius, and J. Hahn. In Silico Identification of Potential Transcriptional Regulators Associated with Human MAPK Signaling. 41st Annual Northeast Bioengineering Conference, Troy, New York (2015)

65. A.S. Bhadouria and J. Hahn. Optimal Experimental Design using Partial Least Squares Regression. 41st Annual Northeast Bioengineering Conference, Troy, New York (2015)

64. D. Howsmon, W. Dai, and J. Hahn. Identifying and Validating Systems Pharmacology Models. ASCPT Workshop on Quantitative Systems Pharmacology: Multiscale Model-Based Drug Development through Integrating Systems Biology and Pharmacometrics, New Orleans, Louisiana (2015) Invited Presentation

63. V. Mahindrakar and J. Hahn. Model Predictive Control of Reactive Distillation for Benzene Hydrogenation. AIChE 2014 Annual Meeting, Atlanta, Georgia (2014)

62. T. Omer, N. Sinsuebphon, L. Zhao, X. Intes, and J. Hahn. Optimization of Time Gate Selection in Bi-exponential Fluorescence Lifetime Imaging via Sensitivity Analysis. BMES 2014 Annual Meeting, San Antonio, Texas (2014)

61. V. Mahindrakar and J. Hahn. Modeling and Control of Benzene Hydrogenation via Reactive Distillation. AIChE's Process Development Symposium, Philadelphia, Pennsylvania (2014) Invited Presentation

60. W. Dai and J. Hahn. Estimation of Transcription Factor Profiles from Fluorescent Protein Reporter Systems. 40th Annual Northeast Bioengineering Conference, Boston, Massachusetts (2014)

59. M. Shah, E. Ledet, and J. Hahn. Effect of Loading Frequency on Trans-endplate Nutrition across the Intervertebral Disc: a Force-Controlled Unconfined Compression Experiment. 40th Annual Northeast Bioengineering Conference, Boston, Massachusetts (2014)

58. M. Sorci, M. Gu, A.S. Bhadouria, C.L. Heldt, E. Grafeld, J. Hahn, G. Belfort, K. Sanderson, and T. Miyabayashi. Advancing Bioprocessing Through Industrial Research Collaboration: Fractionating Proteins and Optimizing Operating Conditions. Recovery of Bioprocesses, Rostock, Germany (2014)

57. M. Shah, H. Guo, E. Ledet, and J. Hahn. Effect of Load Frequency on the Trans-endplate Transport of Nutrients to the Intervertebral Disc. ORS 60th Annual Meeting, New Orleans, Louisiana (2014)

56. W. Dai, L. Bansal, D. Word, and J. Hahn. Parameter Set Selection for Signal Transduction Models with Significant Uncertainties. AIChE 2013 Annual Meeting, San Francisco, California (2013)

55. D. Chaar, J. Hahn, A. Jayaraman, R. Alaniz. Regulatory T-Cell Differentiation Plasticity Model. AIChE 2013 Annual Meeting, San Francisco, California (2013)

54. A. Bhadouria, M. Sorci, M. Gu, G. Belfort, and J. Hahn. Ultrafiltration Optimization via Experimental Design. AIChE 2013 Annual Meeting, San Francisco, California (2013)

53. S. Mailhiot, M. Newman, N. DiNardi, K. Maziarski, E. Baral, T. Hasekioglu, and J. Hahn. Design of a Drug Infusion Controller for Reducing Post-Operative High Blood Pressure. AIChE 2013 Annual Meeting, San Francisco, California (2013)

52. V. Mahindrakar and J. Hahn. Dynamics and Control of Benzene Hydrogenation via Reactive Distillation. AIChE 2013 Annual Meeting, San Francisco, California (2013)

51. S. Tututi-Avila, A. Jimenez-Gutierrez, and J. Hahn. Multi-Loop Control Structure for Dividing-Wall Distillation Columns. AIChE 2013 Annual Meeting, San Francisco, California (2013)

50. T. Omer, N. Sinsuebphon, L. Zhao, X. Intes, and J. Hahn. Optimization of Time Gate Selection for Bi-exponential Fluorescence Lifetime Imaging. BMES 2013 Annual Meeting, Seattle, Washington (2013)

49. V. Mahindrakar and J. Hahn. Dynamics and Control of Benzene Hydrogenation via Reactive Distillation. APM 2013: The Advanced Process Modeling Forum, New York, New York (2013)

48. T. Omer, N. Sinsuebphon, L. Zhao, X. Intes, and J. Hahn. Selection of Temporal Gates for Bi-exponential Fluorescence Lifetime Imaging. 39th Annual Northeast Bioengineering Conference, Syracuse, New York (2013)

47. L. Bansal, A. Jayaraman, and J. Hahn. Computational Techniques for Modeling and Analysis of Fluorescent Protein labeled Cell Populations. BMES 2012 Annual Meeting, Atlanta, Georgia (2012)

46. L. Bansal, S. Maiti, A. Jayaraman, C. Laird, and J. Hahn. Modeling of Fluorescent Protein-Labeled Cell Populations to Analyze Transcriptional and Division Effects on Fluorescent Intensity Distributions. AIChE 2012 Annual Meeting, Pittsburgh, Pennsylvania (2012)

45. S. Maiti, R. Alaniz, J. Hahn, and A. Jayaraman. Modeling Intra- and Inter-Kingdom Signaling Through NF-Kb Pathway in Dendritic Cells. AIChE 2012 Annual Meeting, Pittsburgh, Pennsylvania (2012)

44. W. Dai, D. Word, and J. Hahn. Modeling and Dynamic Optimization of Fuel-Grade Ethanol Fermentation Using Fed-Batch Process. AIChE 2012 Annual Meeting, Pittsburgh, Pennsylvania (2012)

43. L. Bansal, S. Maiti, A. Jayaraman, C. Laird, and J. Hahn. Modeling of Fluorescent Protein-Labeled Cell Populations to Analyze Transcriptional and Division Effects on Fluorescent Intensity Distributions. Foundations of Systems Biology in Engineering 2012, Tsuruoka, Japan (2012)

42. J. Hahn. Use of Systems Biology Concepts for Signal Transduction Pathway Modeling. Workshop on Model-based Analysis and Control of Cellular Processes, West Lafayette, Indiana (2012) Invited Presentation

41. L. Bansal, Y. Chu, C. Laird, and J. Hahn. Regularization of Ill-Conditioned Inverse Problems Resulting From Determining Transcription Factor Profiles From Fluorescent Reporter Images. AIChE 2011 Annual Meeting, Minneapolis, Minnesota (2011)

40. L. Bansal, E. Yang, R. Nelson, A. Jayaraman, and J. Hahn. Experimental Design of Systems Involving Multiple Fluorescent Reporters. AIChE 2011 Annual Meeting, Minneapolis, Minnesota (2011)

39. R. Kaunas, Z. Huang, and J. Hahn. A Kinematic Model Coupling Stress Fiber Dynamics with JNK Activation in Response to Matrix Stretching. AIChE 2011 Annual Meeting, Minneapolis, Minnesota (2011)

38. J. Hahn and D.F. Shantz. REU Site: Materials and Systems Biology Research In Biotechnology and Biomedicine. AIChE 2011 Annual Meeting, Minneapolis, Minnesota (2011)

37. Z. Huang, Y. Chu, L. Bansal, and J. Hahn. Derivation of Transcription Factor Distribution Profiles from Green Fluorescent Protein Reporter Data. AIChE 2010 Annual Meeting, Salt Lake City, Utah (2010) Invited Presentation

36. M. Serpas and J. Hahn. Effect of Soft Sensor Dynamics on Process Monitoring. AIChE 2010 Annual Meeting, Salt Lake City, Utah (2010)

35. C. Moya, Z. Huang, J. Hahn, and A. Jayaraman. Quantitative Determination of Transcription Factor Profiles from Reporter Data. AIChE 2010 Annual Meeting, Salt Lake City, Utah (2010)

34. Y. Chu, Z. Huang, M. Serpas, and J. Hahn. Global Sensitivity Analysis Procedure Accounting for Effect of Available Experimental Data. AIChE 2010 Annual Meeting, Salt Lake City, Utah (2010)

33. Z. Huang, C. Moya, P. Cheng, A. Jayaraman, and J. Hahn. Mathematical Modeling of IL-6 and IL-10 Signal Transduction in Steatosis. AIChE 2009 Annual Meeting, Nashville, Tennessee (2009)

32. Y. Chu and J. Hahn. A New Global Sensitivity Analysis Procedure Involving Quasi Linearization for Optimal Experimental Design. AIChE 2009 Annual Meeting, Nashville, Tennessee (2009)

31. Z. Huang, Y. Chu, and J. Hahn. Derivation of Reduced Models for Signal Transduction Pathways via Sensitivity and Observability Analysis. AIChE 2009 Annual Meeting, Nashville, Tennessee (2009)

30. R. Kaunas, Z. Huang, and J. Hahn. A Kinematic Model Coupling Stress Fiber Dynamics with JNK Activation in Response to Matrix Stretching. 2009 Summer Bioengineering Conference, Lake Tahoe, California (2009)

29. Z. Huang, F. Senocak, A. Jayaraman, and J. Hahn. Quantitative Measurement Technique for Transcription Factor Profiles. AIChE 2008 Annual Meeting, Philadelphia, Pennsylvania (2008)

28. Y. Chu, Z. Huang, and J. Hahn. Analysis Procedure for Signal Transduction Pathways by Clustering Parameters According to their Sensitivity Profiles. AIChE 2008 Annual Meeting, Philadelphia, Pennsylvania (2008)

27. C.Y. Qu and J. Hahn. Computation of Arrival Cost for Moving Horizon Estimation via Unscented Kalman Filtering. AIChE 2008 Annual Meeting, Philadelphia, Pennsylvania (2008)

26. Y. Chu and J. Hahn. Parameter Set Selection Via Clustering of Parameters into Pair-Wise Indistinguishable Groups of Parameters. AIChE 2008 Annual Meeting, Philadelphia, Pennsylvania (2008)

25. Y. Chu, Z. Huang, and J. Hahn. Sensitivity Analysis for Parameter Estimation of Signal Transduction Networks. SIAM Conference on the Life Sciences, Montreal, Canada (2008) Invited Presentation

24. E.P. Gatzke and J. Hahn. Cache Virtual Process Control Book: Online Resources for Graduate Process Control Instruction. AIChE 2007 Annual Meeting, Salt Lake City, Utah (2007)

23. Y. Chu, R. Cox, M. Misra and J. Hahn. Parameter Set Selection for Estimation of Nonlinear Dynamic Systems. AIChE 2007 Annual Meeting, Salt Lake City, Utah (2007)

22. Y. Chu and J. Hahn. Analysis of Interactions among the Components in the Il-6 Signaling Pathways. AIChE 2007 Annual Meeting, Salt Lake City, Utah (2007)

21. Z. Huang and J. Hahn. Development and Comparison of Algorithms for Analysis of Fluorescent Images for Studying the Dynamics of Signal Transduction Pathways. AIChE 2007 Annual Meeting, Salt Lake City, Utah (2007)

20. P. Balbuena, J. Hahn, and V. Ugaz. Integrating Current Research Trends in Undergraduate Education. 2007 Engineering Education NSF Awardees Conference, Arlington, Virginia (2007)

19. C. Qu and J. Hahn. Process Monitoring and Parameter Estimation via Unscented Kalman Filtering. AIChE 2007 Spring National Meeting, Houston, Texas (2007)

18. Y. Chu and J. Hahn. Development of Parameter Sensitivity Analysis Technique for Studying Interactions among Parameters and Application to Systems Biology. 5th International Conference On Differential Equations and Dynamical Systems, Edinburg, Texas (2006) Invited Presentation

17. Y. Chu, A.K. Singh, A. Jayaraman, and J. Hahn. Sensitivity Analysis-Based Approach for Identifying Key Steps in Cell Signaling for Hepatocytes Stimulated by Il-6. AIChE 2006 Annual Meeting, San Francisco, California (2006)

16. A.K. Singh and J. Hahn. Computing Sensor Locations for Nonlinear Systems under the Influence of Disturbances. AIChE 2006 Annual Meeting, San Francisco, California (2006)

15. J. Brewer, A.K. Singh, M. Misra, and J. Hahn. Sensor Network Design Via Observability Analysis and Principal Component Analysis. AIChE 2006 Annual Meeting, San Francisco, California (2006)

14. J. Hahn. Nonlinear Model Reduction and its Application to Model Predictive Control. Conference on Adaptive Model Reduction Methods for PDE Constrained Optimization, Houston, Texas (2006) Invited Presentation

13. C. Sun and J. Hahn. Parameter Reduction for Nonlinear Models Based on Hankel Singular Values and Sensitivity Analysis. AIChE 2005 Annual Meeting, Cincinnati, Ohio (2005)

12. A.K. Singh and J. Hahn. Determining Sensor Locations for Stable Nonlinear Systems: the Multiple Sensor Case. AIChE 2005 Annual Meeting, Cincinnati, Ohio (2005)

11. A.K. Singh, A. Jayaraman, and J. Hahn. Mathematical Model of Il-6 Signal Transduction in Hepatocytes. AIChE 2005 Annual Meeting, Cincinnati, Ohio (2005)

10. U. Kruger, D. Antory, J. Hahn, G.W. Irwin, and G. McCullough. Introduction of a Nonlinearity Measure for Principal Component Models. Symposium on Modeling of Complex Processes, College Station, Texas (2005)

9. A.K. Singh and J. Hahn. State Estimation for High-Dimensional Chemical Processes. Symposium on Modeling of Complex Processes, College Station, Texas (2005)

8. S. Rajaraman, M.S. Mannan, and J. Hahn. Robust Fault Detection, Isolation, and Reconstruction for Nonlinear Processes with Parametric Uncertainties. AIChE 2004 Annual Meeting, Austin, Texas (2004)

7. A. Singh and J. Hahn. Determining Optimal Sensor Locations for Parameter Estimation via Covariance Matrices. AIChE 2004 Annual Meeting, Austin, Texas (2004)

6. C. Sun and J. Hahn. Nonlinear Model Reduction of DAE Systems. AIChE 2004 Annual Meeting, Austin, Texas (2004)

5. A. Singh and J. Hahn. Reduced-Order Observers for High-Dimensional Chemical Processes. AIChE 2004 Annual Meeting, Austin, Texas (2004)

4. J. Hahn, M. Monnigmann, and W. Marquardt. Determining the Effect of Model Uncertainty on Controller and Observer Design via Bifurcation Analysis. AIChE 2003 Annual Meeting, San Francisco, California (2003)

3. J. Hahn. Nonlinear Model Reduction and its Application to Model Predictive Control. Model Reduction for Process Control Workshop, Lund, Sweden (2002) Invited Presentation

2. J. Hahn and T.F. Edgar. Nonlinearity Quantification and Model Classification using Gramians and other Covariance Matrices. AIChE 2001 Annual Meeting, Reno, Nevada (2001)

1. J. Hahn, S. Lextrait, and T.F. Edgar. Nonlinear Balanced Model Residualization via Neural Networks. AIChE 2000 Annual Meeting, Los Angeles, California (2000)