Swank Lab

 

Ramanath, S., Q. Wang, W. A. Kronert, S. I. Bernstein and D. M. Swank. Disrupting the myosin converter-relay interface impairs Drosophila indirect flight muscle performance. Biophysical Journal (in revision).


Clark, K.A., H. Lesage-Horton, M. C. Beckerle and D. M. Swank. Deletion of Drosophila muscle LIM protein decreases flight muscle stiffness and power generation. Amer. J. Physiol.-Cell (in press).


Purcell, T. J., N. Naber, K. Franks-Skiba, A. R. Dunn, C. C. Eldred, C. L. Berger, A. Malnasi-Csizmadia, J. A. Spudich, D. M. Swank, E. Pate, and R. Cooke (2011) Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency. J. Mol. Biol. 407:79-91


Yang, C., C. Kaplan, M. Thatcher and D. M. Swank (2010) The influence of myosin converter and relay domains on cross-bridge kinetics of Drosophila indirect flight muscle. Biophys. J. 99:1546-1555.


Eldred, C.C., D.R. Simeonov, R.A. Koppes, C. Yang, D.T. Corr and D.M. Swank (2010) The mechanical properties of Drosophila jump muscle expressing wild-type and embryonic myosin isoforms. Biophys. J. 98:1218-1226.


Miller, M.S., C. M. Dambacher, A. F. Knowles, J. M. Braddock, G. P. Farman, T. C. Irving, D. M. Swank, S. I. Bernstein and David W. Maughan (2009) Alternative S2 hinge regions of the myosin rod affect myofibrillar structure with minor alterations in myosin kinetics. Biophysical Journal 96:4132-4143.


Yang, C., S. Ramanath, S. I. Bernstein, D. W. Maughan and D.M. Swank (2008) Alternative versions of the myosin relay domain differentially respond to load to influence Drosophila muscle kinetics. Biophysical Journal 95:5228-5237.


Kronert, W.A., C.A. Dambacher, A.F. Knowles, D.M. Swank and S.I. Bernstein (2008) Alternative relay domains of Drosophila melanogaster myosin differentially affect ATPase activity, in vitro motility, myofibril structure and muscle function. J. Mol. Biol. 379:443-456.


Hao, Y., M. S. Miller, D. M. Swank, H. Liu, S. I. Bernstein, D. W. Maughan, G. H. Pollack (2006) Passive stiffness in Drosophila indirect flight muscle is reduced by disrupting paramyosin phosphorylation, but not by embryonic myosin S2 hinge substitution. Biophysical J. 103:17543-17547.


Swank, D.M., V. Vishnudas and D.W. Maughan (2006) An exceptionally fast actomyosin reaction powers insect flight muscle. Proc. Natl. Acad. Sci. 103:17543-17547.


Swank, D.M.,  J. Braddock, W. Brown, H. Lesage, S.I. Bernstein, and D.W. Maughan (2006) An alternative domain near the ATP binding pocket of Drosophila myosin affects muscle fiber kinetics. Biophys. J. 90:2427-2435.


Miller, B.M., S. Zhang, J.A. Suggs, D.M. Swank, K.P. Littlefield, A.F. Knowles and S.I. Bernstein (2005) An alternative domain near the nucleotide-binding site of Drosophila muscle myosin affects ATPase kinetics. J. Mol. Biol. 353:14-25.


Liu, H., M.S. Miller, D.M. Swank, W.A. Kronert, D.W. Maughan and S.I. Bernstein (2005) Paramyosin phosphorylation site disruption affects indirect flight muscle stiffness and power generation in Drosophila melanogaster. Proc. Natl. Acad. Sci. 102:10522-10527.


Swank, D.M., W.A. Kronert, S.I. Bernstein, and D.W. Maughan (2004) Alternative N-terminal regions

of Drosophila myosin heavy chain tune muscle kinetics for optimal power output. Biophys.

87:1805-1814.


Littlefield, K.M., D.M. Swank, B. Sanchez, A.F. Knowles, D. M. Warshaw, and S.I. Bernstein (2003) The converter domain modulates the kinetic properties of Drosophila myosin. Amer. J. of Physiol. 284:C1031-C1038.


Swank, D.M., A.F. Knowles, W.A. Kronert, J.A. Suggs, G.E. Morrill, M. Nikkoy, G.G. Manipon, and S.I. Bernstein (2003) Variable N-terminal regions of muscle myosin heavy chain modulate ATPase rate and actin sliding velocity. J. Biol. Chem. 278:17475-17482.


Swank, D.M., A.F. Knowles, F. Sarsoza, J.A. Suggs, D.W. Maughan and S.I. Bernstein (2002) The myosin converter domain modulates muscle performance. Nature Cell Biology 4: 312-317.


Swank, D.M., M.L. Bartoo, A.F Knowles, C. Iliffe, S.I. Bernstein, J.E. Molloy, and J.C. Sparrow (2001) Alternative exon-encoded regions of Drosophila myosin heavy chain modulate ATPase rates and actin sliding velocity.  J. Biol. Chem 276: 15117-15124.


Rome L.C., and D.M. Swank (2001) The influence of thermal acclimation on power production during swimming I. in vivo stimulation and length change pattern of scup red muscle. J. Exp. Biol. 204: 409-418.


Swank, D.M. and L.C. Rome (2001) The influence of thermal acclimation on power production during swimming II. mechanics of scup red muscle under in vivo conditions. J. Exp. Biol. 204: 419-430.


Swank, D.M., L. Wells, W.K. Kronert, G. Morrill and S.I Bernstein (2000) Determining structure/function relationships for sarcomeric myosin heavy chain by genetic and transgenic manipulation of Drosophila. Microscopy Res. and Tech. 50: 430-442.


Swank, D.M. and L.C. Rome (1999) The influence of temperature on power production during swimming I. in vivo length change and stimulation pattern. J. Exp. Biol. 203: 321-331.


Rome, L.C., D.M. Swank and D.J. Coughlin (1999) The influence of temperature on power production during swimming II. mechanics of red muscle fibers in vivo. J. Exp. Biol. 203: 333-345.


Swank, D.M., G. Zhang, and L.C. Rome (1997) Contraction kinetics of red muscle in scup: mechanism for variation in relaxation rate along the length of the fish. J. Exp. Biol. 200: 1297-1307.


Swank, D.M. and L.C. Rome (1996) Effects of SR calcium pump inhibition on relaxation and power from scup red muscle. Biol. Bull. 191: 267-268.


Zhang, G., D.M. Swank and L.C. Rome (1996) Quantitative distribution of muscle fiber types in the scup Stenotomus chrysops.  J. Morphology 229: 71-81.


Rome, L.C., D.M. Swank and D. Corda (1993) How fish power swimming. Science 261: 340-343.


Rome, L.C., and D. Swank (1992) The influence of temperature on power output of scup red muscle during cyclical length changes. J. Exp. Biol. 171: 261-281


Hong, W.J., J.K. Petell, D. Swank, J. Sanford, D.C. Hixson and D. Doyle (1989) Expression of

Dipeptidyl Peptidase IV is mainly regulated at the mRNA level. Exp. Cell Res. 182: 256-266.


Publications