Selected Publications


Chan DD, Lai L, Butz KD, Nauman EA, Dickerson DA, Jonkers I, Neu CP. 2018. Functional MRI can detect changes in intratissue strains in a full thickness and critical sized ovine cartilage defect model. J Biomech. 3;66:18-25.


Chan DD, Li J, Luo W, Predescu DN, Cole BJ, Plaas A. 2018. Pirfenidone Reduces Subchondral Bone Loss and Fibrosis after Murine Knee Cartilage Injury.  J Orthop Res. 36(1):365-376.


Mashiatulla M, Moran M, Chan DD, Li J, Snyder BD, Grinstaff MW, Plaas A, Sumner DR. 2017. Murine Articular Cartilage Morphology and Compositional Quantification with High Resolution Cationic Contrast enhanced ╬╝CT. J Orthop Res. 35(12):2740-2748.


Chan DD, Cai LY, Butz KD, Trippel SB, Nauman EA, Neu CP. 2016. In vivo articular cartilage deformation: noninvasive quantification of intratissue strain during joint contact in the human knee. Scientific Reports. 6: 19220.


Chan DD, Xiao WF, Li J, de la Motte CA, Sandy JD, Plaas A. 2015. Deficiency of Hyaluronan Synthase 1 (Has1) Results in Chronic Joint Inflammation and Widespread Intra-Articular Fibrosis in a Murine Model of Knee Joint Cartilage Damage. Osteoarthritis and Cartilage. 23(11): 1879-89


Sandy JD, Chan DD, Trevino RL, Wimmer MA, Plaas A. 2015. Human Genome-Wide Expression Analysis Re-Orients the Study of Inflammatory Mediators and Biomechanics in Osteoarthritis. Osteoarthritis and Cartilage. 23(11): 1939-45


Chan DD, Gossett PC, Butz KD, Nauman EA, Neu CP. 2014. Comparison of Intervertebral Disc Displacements Measured Under Applied Loading with MRI at 3.0T and 9.4T. Journal of Biomechanics. 47(11): 2801-6


Chan DD, Neu CP. 2014. Intervertebral Disc Internal Deformation Measured by Displacements Under Applied Loading with MRI (dualMRI) at 3T. Magnetic Resonance in Medicine. 17: 1231-7


Chan DD, Neu CP. 2013. Probing Articular Cartilage Damage and Disease by Quantitative Magnetic Resonance Imaging. Journal of the Royal Society Interface. 10(78): 20120608


Chan DD, Neu CP. 2012. Transient and Microscale Deformations and Strains Measured Under Exogenous Loading by Noninvasive Magnetic Resonance. PLoS ONE. 7(3): e33463


Butz KD, Chan DD, Nauman EA, Neu CP. 2011. Stress Distributions and Material Properties Determined in Articular Cartilage from MRI-based Finite Strains. Journal of Biomechanics. 44(15): 2667-2672


Chan DD, Kahn SN, Ye XJ, Curtiss SB, Gupta MC; Kleinberg EO, Neu CP. 2011. Mechanical and Biochemical Characteristics of Degenerated Rabbit Intervertebral Disc Model Using Magnetic Resonance Imaging. Spine. 36(18): 1438-45


Chan DD, Neu CP, Hull ML. 2009. In Situ Deformation of Cartilage in Cyclically Loaded Tibiofemoral Joints by Displacement-Encoded MRI. Osteoarthritis and Cartilage. 17(11): 1461-1468.


Chan DD, Neu CP, Hull ML. 2009. Articular Cartilage Deformation Determined in an Intact Tibiofemoral Joint by Displacement-Encoded Imaging. Magnetic Resonance in Medicine. 61(4): 989-993