Chan Research Group

Selected Publications


Chan DD, Li J, Luo W, Predescu DN, Cole BJ, Plaas A. 2017. Pirfenidone Reduces Subchondral Bone Loss and Fibrosis after Murine Knee Cartilage Injury.  J Orthop Res. IN PRESS.


Mashiatulla M, Moran M, Chan DD, Li J, Snyder BD, Grinstaff MW, Plaas A, Sumner DR. 2017. Murine Articular Cartilage Morphology and Compositional Quantification with High Resolution Cationic Contrast enhanced ╬╝CT. J Orthop Res. IN PRESS.


Chan DD, Cai LY, Butz KD, Trippel SB, Nauman EA, Neu CP. 2016. In vivo articular cartilage deformation: noninvasive quantification of intratissue strain during joint contact in the human knee. Scientific Reports. 6: 19220.


Chan DD, Xiao WF, Li J, de la Motte CA, Sandy JD, Plaas A. 2015. Deficiency of Hyaluronan Synthase 1 (Has1) Results in Chronic Joint Inflammation and Widespread Intra-Articular Fibrosis in a Murine Model of Knee Joint Cartilage Damage. Osteoarthritis and Cartilage. 23(11): 1879-89


Sandy JD, Chan DD, Trevino RL, Wimmer MA, Plaas A. 2015. Human Genome-Wide Expression Analysis Re-Orients the Study of Inflammatory Mediators and Biomechanics in Osteoarthritis. Osteoarthritis and Cartilage. 23(11): 1939-45


Chan DD, Gossett PC, Butz KD, Nauman EA, Neu CP. 2014. Comparison of Intervertebral Disc Displacements Measured Under Applied Loading with MRI at 3.0T and 9.4T. Journal of Biomechanics. 47(11): 2801-6


Chan DD, Neu CP. 2014. Intervertebral Disc Internal Deformation Measured by Displacements Under Applied Loading with MRI (dualMRI) at 3T. Magnetic Resonance in Medicine. 17: 1231-7


Chan DD, Neu CP. 2013. Probing Articular Cartilage Damage and Disease by Quantitative Magnetic Resonance Imaging. Journal of the Royal Society Interface. 10(78): 20120608


Chan DD, Neu CP. 2012. Transient and Microscale Deformations and Strains Measured Under Exogenous Loading by Noninvasive Magnetic Resonance. PLoS ONE. 7(3): e33463


Butz KD, Chan DD, Nauman EA, Neu CP. 2011. Stress Distributions and Material Properties Determined in Articular Cartilage from MRI-based Finite Strains. Journal of Biomechanics. 44(15): 2667-2672


Chan DD, Kahn SN, Ye XJ, Curtiss SB, Gupta MC; Kleinberg EO, Neu CP. 2011. Mechanical and Biochemical Characteristics of Degenerated Rabbit Intervertebral Disc Model Using Magnetic Resonance Imaging. Spine. 36(18): 1438-45


Chan DD, Neu CP, Hull ML. 2009. In Situ Deformation of Cartilage in Cyclically Loaded Tibiofemoral Joints by Displacement-Encoded MRI. Osteoarthritis and Cartilage. 17(11): 1461-1468.


Chan DD, Neu CP, Hull ML. 2009. Articular Cartilage Deformation Determined in an Intact Tibiofemoral Joint by Displacement-Encoded Imaging. Magnetic Resonance in Medicine. 61(4): 989-993