Breast and Ovarian Cancer Development
The "RING Finger" structural motif is Cys3HisCys4. Mutations in one of these, which interacts with the breast and ovarian cancer gene BRCA1, have been implicated in the development of breast and ovarian cancer.
For more information regarding the BRCA1 gene in breast and ovarian cancers, follow the links below:
Breast Cancer Overview
Ovarian Cancer Overview