CHIME EXERCISE

E. coli Ribonucleotide Reductase Structures

3R1R: R1 subunit Ribonucleotide Reductase

4R1R: R1 subunit Ribonucleotide Reductase

1RIB: R2 subunit Ribonucleotide Reductase

 

 

 

1AV8: Ribonucleotide Reductase

The structure to the right is of the R2 subunit of E. coli Ribonucleotide Reductase.  The biological molecule consists of a heterotetramer of 2 a- and

two b- chains.

 

 

In the structure to the right, identify the following properties:

 

  • 8 long a-helices in one unit of R2

  • Tyr122 residue

  • The binuclear Fe (III) complex

  • The ligands of the Fe (III) complex